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In my opinion, Palutena ought to fight this Boss character instead.
Palutena's Classic Mode route in Super Smash Bros. Ultimate is called "A Little Divine Intervention". According to the Super Smash Bros. wiki, "Palutena's opponents all come from series where religion and mythology play a key role." ...That is, all but the Final Round with Master Hand.
I don't consider Master Hand & Crazy Hand to be the suitable boss characters for this Classic Mode, as they don't really fit the theme...much? Maybe if the Hands were fought at the Palutena's Temple ? form instead of Final Destination...?
However, Ganon would probably be a better choice because he fits the theme as much as Zelda & Link do in Round 1; it could feel as if she went full circle, starting and ending with fighting Zelda characters and Ganon would fit better with Kid Icarus' mythological themes than Dracula would. Also, I personally think that playful goddess would have more fun fighting such a Minotaur than a vampire beast. Heck, if Ganon wasn't so wild, Hades could invite him over for tea and scones.
If there were ever to be an update for SSBU that would change the Boss character for Classic Modes, Palutena ought to fight this guy instead.